Morphological characterization of SARS-CoV-2 through electronic microscopy

  1. Robison Buitrago-Sierra
  2. Álvaro Guzmán
  3. Juan Felipe Santa-Marín
Revista:
TecnoLógicas

ISSN: 2256-5337,  0123-7799

Año de publicación: 2021

Volumen: 24

Número: 50

Tipo: Artículo

DOI: 10.22430/22565337.1675 DIALNET GOOGLE SCHOLAR lock_openDialnet editor

Otras publicaciones en: TecnoLógicas

Resumen

This paper reviews the available literature on the morphological characterization of the SARS-CoV-2 virus by electron microscopy. It presents the most relevant technical aspects for the preparation of samples used by various authors in the field because the details related to said preparation are decisive to obtain the images. In addition, it addresses biosecurity-related factors. Finally, the main morphological characteristics of the virus are described based on the images found in the literature. The morphology of the virus is characterized by a crown-like shape on its surface. Such crowns are composed of spikes and other proteins, forming layers on the surface that are used to penetrate and bind to host cells through the cell membrane.

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